Trypanosome mitochondria rely on an RNA-editing process that rewrites transcripts through precisely timed uridine deletions and insertions, guided by complementary RNAs. For decades, researchers have known the editing is executed by a fast-moving, multi-enzyme system—but how the components coordinate their actions has been difficult to pin down. Now, Liu and colleagues provide structural snapshots of … Continue reading Structure Reveals How Trypanosome Mitochondria Coordinate RNA Editing Cascade