Selecting most effective materials for dental pulp tissue engineering


Credit: Mary Ann Liebert, Inc., publishers

New Rochelle, NY, Aug. 23, 2017–To regenerate dental pulp tissue after emptying of a tooth's root canals researchers compared the effectiveness of 3D scaffolds made of natural or customized synthetic materials containing pulpal stem cells and dentin-derived growth factors. The substantial differences in terms of scaffold degradation, cell viability, vascularization, and pulpal tissue formation are reported in Tissue Engineering, Part A, peer-reviewed journal from Mary Ann Liebert, Inc., publishers . The article is available free on the Tissue Engineering website until September 23, 2017.

The article entitled "Suitability of Different Natural and Synthetic Biomaterials for Dental Pulp Tissue Engineering," was coauthored by Kerstin Galler, DDS, PhD, Ferdinand Brandl, PhD, Susanne Kirchhof, PhD, Matthia Widbiller, DDS, Andreas Eidt, Wolfgang Buchalla, DDS, PhD, Achim Göpferich, PhD, and Gottfried Schmalz, DDS, PhD, University Hospital Regensburg, Germany and University of Bern, Switzerland. The researchers developed a customized, bioactive polyethylene (PEG) derivative and directly compared the PEG-based hydrogel scaffolds to various natural materials including fibrin and collagen.

"Using effective and comprehensive modeling, the authors have differentiated the functionality of dental pulp engineering between synthetic and natural matrices, with the advantage held by the latter," says Tissue Engineering Co-Editor-in-Chief Peter C. Johnson, MD, Principal, MedSurgPI, LLC and President and CEO, Scintellix, LLC, Raleigh, NC.


About the Journal

Tissue Engineering is an authoritative peer-reviewed journal published monthly online and in print in three parts: Part A, the flagship journal published 24 times per year; Part B: Reviews, published bimonthly, and Part C: Methods, published 12 times per year. Led by Co-Editors-In-Chief Antonios G. Mikos, PhD, Louis Calder Professor at Rice University, Houston, TX, and Peter C. Johnson, MD, Principal, MedSurgPI, LLC and President and CEO, Scintellix, LLC, Raleigh, NC, the Journal brings together scientific and medical experts in the fields of biomedical engineering, material science, molecular and cellular biology, and genetic engineering. Leadership of Tissue Engineering Parts B (Reviews) and Part C (Methods) is provided by John P. Fisher, PhD, University of Maryland and John A. Jansen, DDS, PhD, Radboud University, respectively. Complete tables of content and a sample issue may be viewed online at the Journal website. Tissue Engineering is the official journal of the Tissue Engineering & Regenerative Medicine International Society (TERMIS). Complete tables of content and a sample issue may be viewed on the Tissue Engineering website.

About the Publisher

Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including Stem Cells and Development, Human Gene Therapy, and Advances in Wound Care. Its biotechnology trade magazine, GEN (Genetic Engineering & Biotechnology News) was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 80 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website.

Media Contact

Kathryn Ryan
[email protected]

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