Scientists unlock crops’ power to resist floods


Tweaking proteins in staple foods could help feed a warming world


Credit: University of Oxford/PNAS

Enzymes that control a plant’s response to lower oxygen levels could be manipulated to make vital crops resistant to the impacts of flooding triggered by climate change, new research shows.

Co-author Dr Mark White in the School of Chemistry at the University of Sydney said: “Climate change is a major global issue, not least for its impact on food security. We hope these findings can help produce flood-tolerant crops to help mitigate the devasting social and economic impact of extreme weather events on food production.”

The research, largely done at the University of Oxford, is published today in the Proceedings of the National Academy of Sciences of the United States of America.

Climate change has increased the number and intensity of global flooding events, threatening food security through significant crop loss. Plants, including staple crops such as rice, wheat and barley, can survive temporary periods of flooding by activating energy pathways that don’t rely on air in response to the low oxygen conditions in water.

These responses are controlled by oxygen-sensing enzymes called the Plant Cysteine Oxidases (PCOs), which use oxygen to regulate the stability of proteins that control gene activity.

The research describes the molecular structures of the PCOs for the first time, identifying chemical features that are required for enzyme activity.

“The results provide a platform for future efforts to manipulate the enzyme function in an attempt to create flood-resistant crops that can mitigate the impact of extreme weather events,” Dr White said.


Dr White joined the University of Sydney last year as an Australian Research Council Discovery Early Career Research Award recipient. He was previously a postdoctoral researcher at Novo Nordisk, Denmark, and worked at the University of Oxford’s Chemistry Research Laboratory with Dr Emily Flashman, lead researcher on the Plant Cysteine Oxidases paper published today.

DOWNLOAD images of the research and a photo of Dr White at this link.

RESEARCH available upon request.


Dr Mark White

ARC DECRA Research Fellow, School of Chemistry

The University of Sydney

[email protected]


Marcus Strom | [email protected] | +61 423 982 485


This work was supported by the UK Biotechnology and Biological Research Council New Investigator Grant, the European Research Council and the Italian Ministry of Education University and Research.

Media Contact
Marcus Strom
[email protected]

Related Journal Article

Leave A Reply

Your email address will not be published.