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Rewrite Decreased endothelial micro-RNA-30b-5p impairs angiogenesis in fetal lambs with persistent pulmonary hypertension as a headline for a science magazine post, using no more than 8 words

May 6, 2025
in Technology and Engineering
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Impaired angiogenesis contributes to increased pulmonary vascular resistance in persistent pulmonary hypertension of the newborn (PPHN). Notch signaling, critical to lung angiogenesis, is modulated by micro-RNAs (miR). RNA sequencing of pulmonary arterial endothelial cells (PAEC) from a PPHN lamb model revealed downregulated miR-30b-5p.

Sati, S.K., Rana, U., Joshi, C. et al. Decreased endothelial micro-RNA-30b-5p impairs angiogenesis in fetal lambs with persistent pulmonary hypertension.
Pediatr Res (2025). https://doi.org/10.1038/s41390-025-04098-7

https://doi.org/10.1038/s41390-025-04098-7 bu içeriği en az 2500 kelime olacak şekilde ve alt başlıklar ve madde içermiyecek şekilde ünlü bir science magazine için İngilizce olarak yeniden yaz. Teknik açıklamalar içersin ve viral olacak şekilde İngilizce yaz. Haber dışında başka bir şey içermesin. Haber içerisinde en az 14 paragraf ve her bir paragrafta da en az 80 kelime olsun. Cevapta sadece haber olsun. Ayrıca haberi yazdıktan sonra içerikten yararlanarak aşağıdaki başlıkların bilgisi var ise haberin altında doldur. Eğer bilgi yoksa ilgili kısmı yazma.:

Subject of Research:

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Sati, S.K., Rana, U., Joshi, C. et al. Decreased endothelial micro-RNA-30b-5p impairs angiogenesis in fetal lambs with persistent pulmonary hypertension.
Pediatr Res (2025). https://doi.org/10.1038/s41390-025-04098-7

Image Credits: AI Generated

DOI: https://doi.org/10.1038/s41390-025-04098-7

Keywords:

Tags: endothelial micro-RNAsfetal lamb modelimpaired angiogenesismicro-RNA-30b-5pmolecular mechanisms of PPHNneonatal lung developmentNotch signaling in angiogenesispersistent pulmonary hypertensionpulmonary arterial endothelial cellspulmonary vascular resistancetherapeutic targets in hypertensionvascular biology research
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