Reading histone modifications, an oncoprotein is modified in return

(American Society for Biochemistry and Molecular Biology) Turning genes on and off is an intricate process involving communication between many different types of proteins that interact with DNA. These communications can go awry, resulting in conditions like cancer. Researchers at the University of Texas MD Anderson Cancer Center have uncovered an unusual form of cross-talk between proteins that affect gene expression, suggesting new ways of inhibiting metastasis in cancer. The findings are published in the Journal of Biological Chemistry.