Overweight affects DNA methylation


(Helmholtz Zentrum München – German Research Center for Environmental Health) The extra pounds you gain during the holidays will not only show up on your hips but will also affect your DNA. This is the result of a large-scale international study coordinated by Helmholtz Zentrum München, a partner in the German Center for Diabetes Research, which has now been published in 'Nature.' The study shows that a high BMI leads to epigenetic changes at nearly 200 loci of the genome — with effects on gene expression.

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