Opioid overdose responsible for over 500,000 years of life lost in Ohio

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Credit: The Ohio Alliance for Innovation in Population Health

ATHENS, Ohio (June 14, 2018) – More than 500,000 years of life expectancy were lost in Ohio during a seven-year period, according to a study conducted by The Ohio Alliance for Innovation in Population Health (OAIPH) — a collaborative initiative formed by Ohio University's College of Health Sciences and Professions and the University of Toledo's College of Health and Human Services.

As opioid overdose continues to increase as a cause of preventable mortality in the state, the OAIPH set out to examine how opioid overdose deaths contribute to increased mortality and to shine a light on the effect of the epidemic on the lifespan of Ohioans at the state and county level. "This data gives us a picture of the profound impact of opioid related deaths," said Rick Hodges, director of OIAPH. "These are people in the prime of life during their most productive years. The data also tells a story about families and communities."

The years of life lost (YLL) was calculated from data abstracted from the Ohio Department of Health, Bureau of Vital Statistics, Ohio Death Certificate File for the years 2010-2016. YLL due to premature death were calculated at the state and county level and patterns of opioid overdose mortality were mapped geographically and monitored over time.

A number of key findings stand out in the study:

  • 13,059 Ohioans died from opioid overdose during the 7-year period of study (2010 – 2016).
  • Opioid overdose accounted for 519,471 YLL from 2010 – 2016. This figure represents over half a million years of life lost to Ohioans due to a preventable cause.
  • Opioid overdose deaths continue to rise. 140,045 YLL were attributable to opioid overdose in 2016 alone. That year, opioid overdose had the effect of lowering the life expectancy of an average Ohioan by 1.1 years.
  • Fentanyl related deaths have increased dramatically in recent years from 77 deaths in 2010 to 2,357 in 2016.
  • Fentanyl was involved in 67 percent of fatal opioid poisonings in 2016 and fentanyl overdose accounted for 96,118 YLL that year alone.

"One of the most heartbreaking aspects of the opioid epidemic is the incredible loss of life as so many young people die of overdoses," said Randy Leite, dean of the OHIO College of Health and Sciences and Professions. "The years of life lost data paint a picture of the greatest consequence of the epidemic — the loss of so many individuals who could have been productive parents, spouses, workers, and citizens."

"These numbers are staggering. Ohio University has made a commitment to provide resources to help reverse the rising tide of the opioid epidemic," added President M. Duane Nellis. "This study is one example of the work that we are accomplishing to meet this important priority." Nellis recently created the Opioid Task Force, comprised of both community members and University faculty, staff and administrators from the Athens and Regional Campuses, to collectively elevate the impact of the region's opioid-related initiatives.

Of the Task Force, Nellis said, "We can make significant progress in combatting this epidemic in a concerted, coordinated manner and leverage our collective expertise to save lives and enact real change toward the betterment of our region."

Brief Methodology

Years of Life Lost (YLL) was determined for fatal opioid overdose decedents in Ohio from 2010 through 2016. This was accomplished via a standardized protocol employed by the World Health Organization Global Burden of Disease Study.2,3 The age at death for each decedent was subtracted from the standard life expectancy accounting for gender. Life expectancy was determined from the Social Security Administration Period Life Table.4 Data used for this analysis were provided by the Ohio Department of Health.

The analysis demonstrates that opioid overdose is an increasing cause of preventable death in Ohio with a measurable impact on life expectancy and reveals temporal and geographic patterns in opioid overdose mortality across the state. Opioid overdose accounted for over half a million years of potential life lost to Ohioans during the seven-year period of study. Total YLL increased annually during this timeframe with fentanyl-involved poisonings accounting for a growing proportion of this premature mortality. Opioid overdose led to a decrement of 1.1 years in average life expectancy in Ohio in the year 2016. Opioid overdose mortality is not evenly distributed within the state. Significant regional variation exists with regard to premature death due to opioid poisoning. Our findings may be used to guide resource allocation with regard to preventative health measures and inform future research.

<p>Table One: Years of Life Lost Due to Opioid Overdoses from 2010 through 2016</p>  <p>Death   Total   Avg Years   Avg Years   Total Years   <br />Deaths  Lost per    Lost per    Lost for      <br />DecedentDecedent    All Decedents     <br />Mean    Median        <br />2010    980 39.51   38.66   38,720    <br />2011    1,163   39.16   38.53   45,543    <br />2012    1,272   39.88   39.46   50,727    <br />2013    1,539   39.06   38.53   60,113    <br />2014    2,020   39.59   40.38   79,972    <br />2015    2,590   40.29   41.31   104,351   <br />2016    3,495   40.07   41.31   140,045   <br />Total   13,059  39.78   40.38   519,471 </p>    <p>Table Two: Years of Life Lost Due to Fentanyl and Fentanyl Analog      

Overdoses from 2010 through 2016

Death Total Avg Years Avg Years Total Years
Deaths Lost per Lost per Lost for
Decedent Decedent All Decedents
Mean Median
2010 77 37.63 38.53 2,898
2011 73 36.64 33.16 2,675
2012 75 36.81 33.98 2,761
2013 84 37.88 37.61 3,182
2014 503 41.84 43.17 21,046
2015 1,155 41.35 42.24 47,759
2016 2,357 40.78 42.24 96,118
Total 4,324 40.8 42.24 176,438

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<p><strong>References:</strong></p>     <p>1.   Ohio Death Certificate File. In: Ohio Department of Health BoVS, ed2010 - 2016.  
  1. Murray CJ, Acharya AK. Understanding DALYs (disability-adjusted life years). Journal of health economics. 1997;16(6):703-730.

  2. Struijk EA, May AM, Beulens JW, et al. Development of methodology for disability-adjusted life years (DALYs) calculation based on real-life data. PLoS One. 2013;8(9):e74294.

  3. Administration USSS. Period Life Table, 2013. https://www.ssa.gov/oact/STATS/table4c6.html.

    Years of Life Lost Due to Opioid Overdose in Ohio
    O. Trent Hall, DO, University of Michigan
    Orman Hall, MA, Ohio University
    Ryan P. McGrath, PhD, North Dakota State University
    Sebastian Diaz, PhD, Ohio University
    Zelalem T. Haile, PhD, MPH, Ohio University
    John Hoag, PhD, Ohio University

    Media Contact

    Jim Sabin
    [email protected]
    740-593-0858

http://www.ohio.edu/ucm/media

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