Thursday, May 26, 2022
SCIENMAG: Latest Science and Health News
No Result
View All Result
  • Login
  • HOME PAGE
  • BIOLOGY
  • CHEMISTRY AND PHYSICS
  • MEDICINE
    • Cancer
    • Infectious Emerging Diseases
  • SPACE
  • TECHNOLOGY
  • CONTACT US
  • HOME PAGE
  • BIOLOGY
  • CHEMISTRY AND PHYSICS
  • MEDICINE
    • Cancer
    • Infectious Emerging Diseases
  • SPACE
  • TECHNOLOGY
  • CONTACT US
No Result
View All Result
Scienmag - Latest science news from science magazine
No Result
View All Result
Home Latest News

New study reveals the effect of extended space flight on astronauts’ brains

May 5, 2022
in Latest News
0
Share on FacebookShare on Twitter

Long-duration space flight alters fluid-filled spaces along veins and arteries in the brain, according to new research from Oregon Health & Science University and scientists across the country.

The study published today in the journal Scientific Reports.

“These findings have important implications as we continue space exploration,” said senior author Juan Piantino, M.D., assistant professor of pediatrics (neurology) in the OHSU School of Medicine. “It also forces you to think about some basic fundamental questions of science and how life evolved here on Earth.”

The research involved imaging the brains of 15 astronauts before and after extended tours of duty on the International Space Station.

Researchers used magnetic resonance imaging to measure perivascular space — or the space around blood vessels — in the brains of astronauts prior to their launch and again immediately after their return. They also took MRI measurements again at one, three and six months after they had returned. Astronauts’ images were compared with those taken of the same perivascular space in the brains of 16 Earth-bound control subjects.

Comparing before and after images, they found an increase in the perivascular spaces within the brains of first-time astronauts, but no difference among astronauts who previously served aboard the space station orbiting earth.

“Experienced astronauts may have reached some kind of homeostasis,” Piantino said.  

In all cases, scientists found no problems with balance or visual memories that might suggest neurological deficits among astronauts, despite the differences measured in the perivascular spaces of their brains.

In comparing a large group of deidentified astronauts, the study is the first to comparatively assess an important aspect of brain health in space.

Brains in space

Human physiology is based on the fact that life evolved over millions of years while tethered to Earth’s gravitational pull. Unbound by the forces of gravity, the normal flow of cerebrospinal fluid in the brain is altered in space.

“We all adapted to use gravity in our favor,” Piantino said. “Nature didn’t put our brains in our feet — it put them high up. Once you remove gravity from the equation, what does that do to human physiology?”

Researchers decided to find out by measuring perivascular spaces, where cerebrospinal fluid flows in the brain.

These spaces are integral to a natural system of brain cleansing that occurs during sleep. Known as the glymphatic system, this brain-wide network clears metabolic proteins that would otherwise build up in the brain. Scientists say this system seems to perform optimally during deep sleep. 

The perivascular spaces measured in the brain amount to the underlying “hardware” of the glymphatic system. Enlargement of these spaces occurs in aging, and also has been associated with the development of dementia.

Researchers used a technique developed in the laboratory of co-author Lisa C. Silbert, M.D., M.C.R., professor of neurology in the OHSU School of Medicine, to measure changes in these perivascular spaces through MRI scans.

Piantino said the study could be valuable in helping to diagnose and treat Earth-bound disorders involving cerebrospinal fluid, such as hydrocephalus.

“These findings not only help to understand fundamental changes that happen during space flight, but also for people on Earth who suffer from diseases that affect circulation of cerebrospinal fluid,” Piantino said.

In addition to Piantino and Silbert, co-authors included first authors Kathleen E. Hupfeld and Sutton B. Richmond of the University of Florida; Heather R. McGregor and Rachael D. Seidler of the University of Florida; Daniel L. Schwartz and Madison N. Luther of OHSU; Nichole E. Beltran, Igor S. Kofman, Yiri E. De Dios and Ajitkumar P. Mulavara of PBR in Houston; Roy F. Riascos of the University of Texas Health Science Center; Scott J. Wood and Jacob J. Bloomberg of NASA; and Jeffrey J. Iliff of the University of Washington School of Medicine and the VA Puget Sound Health Care System.

The research was supported by the National Aeronautics and Space Administration, grant NNX11AR02G; the National Space Biomedical Research Institute, award NCC 9-58; the National Science Foundation Graduate Research Fellowship, grants DGE-1315138 and DGE-1842473; the National Institute of Neurological Disorders and Stroke, grant T32-NS082128; the National Institute on Aging fellowship 1F99AG068440 and grant awards R01AG056712, P30AG008017 and P30AG066518; and the National Heart Lung and Blood Institute, grant K23HL150217-01.

The co-authors also thank all of the astronauts who volunteered their time, without whom this project would not have been possible.



Journal

Scientific Reports

DOI

10.1038/s41598-022-11593-y

Method of Research

Imaging analysis

Subject of Research

People

Article Title

Longitudinal MRI‑visible perivascular space (PVS) changes with long‑duration spacefight

Article Publication Date

5-May-2022

Tags: astronautsbrainseffectextendedflightrevealsspacestudy
Share26Tweet16Share5ShareSendShare
  • Asymptomatic SARS-CoV-2 infections responsible for spreading of COVID-19 less than symptomatic infections

    Asymptomatic SARS-CoV-2 infections responsible for spreading of COVID-19 less than symptomatic infections

    68 shares
    Share 27 Tweet 17
  • Congratulations to the 2022 American Ornithological Society (AOS) award winners

    67 shares
    Share 27 Tweet 17
  • University of Kentucky receives renewed $11.4 million grant to further cancer research

    67 shares
    Share 27 Tweet 17
  • Body weight influences the chance of developing Polycystic Ovary Syndrome

    67 shares
    Share 27 Tweet 17
  • Hertz Foundation announces 2022 Hertz fellows

    66 shares
    Share 26 Tweet 17
  • New NYU Abu Dhabi research could make cancer treatments more efficient

    66 shares
    Share 26 Tweet 17
ADVERTISEMENT

About us

We bring you the latest science news from best research centers and universities around the world. Check our website.

Latest NEWS

Data contradict fears of COVID-19 vaccine effects on pregnancy and fertility

Charging a green future: Latest advancement in lithium-ion batteries could make them ubiquitous

Long-duration energy storage beats the challenge of week-long wind-power lulls

Subscribe to Blog via Email

Enter your email address to subscribe to this blog and receive notifications of new posts by email.

Join 188 other subscribers

© 2022 Scienmag- Science Magazine: Latest Science News.

No Result
View All Result
  • HOME PAGE
  • BIOLOGY
  • CHEMISTRY AND PHYSICS
  • MEDICINE
    • Cancer
    • Infectious Emerging Diseases
  • SPACE
  • TECHNOLOGY
  • CONTACT US

© 2022 Scienmag- Science Magazine: Latest Science News.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
Posting....