A new multi-omic study has mapped how the human testicular niche remodels when androgen signaling is abruptly removed, offering a molecular view of what Sertoli cells do when their usual hormonal cues vanish. Published in Nature Communications in 2026, the work analyzes androgen-deprived testes using paired layers of transcriptomic and additional omic measurements, then integrates … Continue reading Multi-omics Study Uncovers How Androgen Deprivation Reprograms Testis Sertoli Cells