Monday, January 30, 2023
SCIENMAG: Latest Science and Health News
No Result
View All Result
  • Login
  • HOME PAGE
  • BIOLOGY
  • CHEMISTRY AND PHYSICS
  • MEDICINE
    • Cancer
    • Infectious Emerging Diseases
  • SPACE
  • TECHNOLOGY
  • CONTACT US
  • HOME PAGE
  • BIOLOGY
  • CHEMISTRY AND PHYSICS
  • MEDICINE
    • Cancer
    • Infectious Emerging Diseases
  • SPACE
  • TECHNOLOGY
  • CONTACT US
No Result
View All Result
Scienmag - Latest science news from science magazine
No Result
View All Result
Home Latest News

Maternal COVID-19 infection increases risks of preterm birth, low birth weight and stillbirth

January 14, 2022
in Latest News
0
Share on FacebookShare on Twitter

People who contracted COVID-19 while pregnant were more likely to have poor birth outcomes including preterm birth, small for gestational age, low birth weight, and stillbirth. The poor outcomes of preterm birth and stillbirth were observed primarily with those infected with SARS-CoV-2 during the first or second trimester, whereas increased rates of small for gestational age were driven largely by third trimester infection.

An Institute for Systems Biology-led study examined the electronic health records of more than 18,000 people with SARS-CoV-2 tests during pregnancy. Researchers compared outcomes of unvaccinated people with a positive test during pregnancy – 882 in total – to those who tested negative.

“We found that SARS-CoV-2 infection indicated increased rates of preterm delivery and stillbirth, largely driven by first and second trimester infections,” said Samantha Piekos, PhD, first author of the study. She added: “The single greatest predictor of gestational age at delivery is gestational age at infection, with earlier age at infection associated with earlier age at delivery.”

The people in the study had mild or moderate SARS-CoV-2 infections. Severity of maternal COVID-19 infection was not correlated with gestational age at delivery. Additionally, poor birth outcomes were present even if maternal COVID-19 didn’t result in severe respiratory problems during infection.

The findings were published today in the journal The Lancet Digital Health and are among the first that account for the trimester of SARS-CoV-2 infection on birth outcomes. 

People in the SARS-CoV-2-positive cohort were more likely to have Hispanic ethnicity, race other than Asian or White, Medicaid insurance, lower age, higher BMI, lower education attainment, and other factors known to be associated with negative birth outcomes. To account for this and to make a true apples-to-apples comparison, researchers used a statistical matching technique that controlled for the confounding variables.

“Pregnant people are at an increased risk of adverse outcomes following SARS-CoV-2 infection, even when maternal COVID-19 is less severe, and they may benefit from increased monitoring following infection,” said Jennifer Hadlock, MD, corresponding author of the paper and assistant professor at ISB. “Both maternal and fetal health are at increased risk with COVID-19. Therefore, this reinforces the importance of protecting pregnant women,” she added.

The study was conducted before COVID-19 vaccines were widely available in the United States. There is an opportunity for future studies to examine whether vaccination helps to prevent negative birth outcomes in breakthrough cases.

This research project was a collaboration between ISB and Providence. 

About ISB

Institute for Systems Biology (ISB) is a Seattle-based non-profit biomedical research organization. We focus on some of the most pressing issues in human health, including aging, autoimmune diseases, brain health, cancer, and many infectious diseases. ISB is an affiliate of Providence, one of the nation’s largest not-for-profit health care systems. Follow us at www.isbscience.org and on YouTube, Facebook, LinkedIn and Twitter.

 



Journal

The Lancet Digital Health

Subject of Research

People

Article Title

The effect of maternal SARS-CoV-2 infection timing on birth outcomes: a retrospective multicentre cohort study

Article Publication Date

13-Jan-2022

Tags: birthCOVID19increasesinfectionmaternalpretermrisksstillbirthweight
Share26Tweet16Share4ShareSendShare
  • Logo

    New study shows snacking on mixed tree nuts may impact cardiovascular risk factors and increase serotonin

    103 shares
    Share 41 Tweet 26
  • Null results research now published by major behavioral medicine journal

    533 shares
    Share 213 Tweet 133
  • New study debunks the assumption that menstrual cycles disqualify women from exercise research

    65 shares
    Share 26 Tweet 16
  • Constructor University professor publishes outstanding psychological research paper

    76 shares
    Share 30 Tweet 19
  • Ignoring Native American data perpetuates misleading white ‘deaths of despair’ narrative, study finds

    67 shares
    Share 27 Tweet 17
  • The next generation of global health innovators: Michelson Prize winners announced

    66 shares
    Share 26 Tweet 17
ADVERTISEMENT

About us

We bring you the latest science news from best research centers and universities around the world. Check our website.

Latest NEWS

New study shows snacking on mixed tree nuts may impact cardiovascular risk factors and increase serotonin

Hydrogen peroxide from tea and coffee residue: New pathway to sustainability

Null results research now published by major behavioral medicine journal

Subscribe to Blog via Email

Enter your email address to subscribe to this blog and receive notifications of new posts by email.

Join 205 other subscribers

© 2022 Scienmag- Science Magazine: Latest Science News.

No Result
View All Result
  • HOME PAGE
  • BIOLOGY
  • CHEMISTRY AND PHYSICS
  • MEDICINE
    • Cancer
    • Infectious Emerging Diseases
  • SPACE
  • TECHNOLOGY
  • CONTACT US

© 2022 Scienmag- Science Magazine: Latest Science News.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In