Infrared sensor as new method for drug discovery

(Ruhr-University Bochum) Using an infrared sensor, biophysicists at Ruhr-Universität Bochum (RUB) have succeeded in analysing quickly and easily which active agents affect the structure of proteins and how long that effect lasts. Thus, Prof Dr Klaus Gerwert and Dr Jörn Güldenhaupt performed time-resolved measurements of the changes to the structure of protein scaffolds, which were triggered by the active agents. Their methods might help develop drugs with little side effects in a quick and targeted manner.

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