Immunotherapy for deadly bacteria shows early promise

(Lehigh University) Lehigh University's Marcos Pires and his team have designed a strategy aimed at tagging Gram-negative bacteria for destruction via small molecule conjugates they have created that specifically home to bacterial cell surfaces and trigger an immune response. They observed a significant decrease in the number of live bacteria using their compound in experiments on E. coli in human serum. The researchers describe their work in a forthcoming paper in Cell Chemical Biology.

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