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How does COVID-19 affect people’s ability to smell

March 23, 2022
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A decreased or altered sense of smell—called olfactory dysfunction—is a common symptom experienced by individuals with COVID-19. As described in an article published in The Laryngoscope, researchers recently searched the medical literature for studies reporting changes in olfactory structures detected through imaging tests of patients with COVID-19.

The prevalence of an olfactory cleft abnormality was nearly 16-fold higher in patients with COVID-19 and olfactory dysfunction (63%) compared with controls (4%). The olfactory clefts provide a crucial channel for airborne molecules to reach sensory olfactory neurons that connect to the brain to enable a person to perceive smells.

“Before this study, most scientists thought that the loss of smell in COVID-19 was mainly due to inflammation and damage to the olfactory nerves. Now, we have compiled evidence from medical imaging that COVID-19 loss of smell is also due to swelling and blockage of the passages in the nose that conduct smells,” said senior author Neville Wei Yang Teo, MRCS, MMed, of Singapore General Hospital.

“We think this is good news for patients who want to recover their sense of smell, since these blockages are expected to resolve with time, while nerve damage in comparison would likely be more difficult to recover from,” added lead author Claire Jing-Wen Tan, of the National University of Singapore. “These findings may not fully account for those who suffer from prolonged olfactory dysfunction, however, and further studies that evaluate patients in this group may provide more information.”

URL Upon Publication: https://onlinelibrary.wiley.com/doi/10.1002/lary.30078

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NOTE: The information contained in this release is protected by copyright. Please include journal attribution in all coverage. For more information or to obtain a PDF of any study, please contact:

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About the Journal

The Laryngoscope is the leading source of information on advances in the diagnosis and treatment of head and neck disorders.

About Wiley

Wiley is a global leader in research and education, unlocking human potential by enabling discovery, powering education, and shaping workforces. For over 200 years, Wiley has fueled the world’s knowledge ecosystem. Today, our high-impact content, platforms, and services help researchers, learners, institutions, and corporations achieve their goals in an ever-changing world. Visit us at  Wiley.com, like us on Facebook and follow us on Twitter and LinkedIn.



Journal

The Laryngoscope

DOI

10.1002/lary.30078

Article Title

Neuroradiological Basis of COVID-19 Olfactory Dysfunction: A Systematic Review and Meta-analysis

Article Publication Date

23-Mar-2022

Tags: abilityaffectCOVID19peoplessmell
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