FDA researchers report first evidence of ESBL producing E. Coli in US retail meat


Credit: Mary Ann Liebert, Inc., publishers

New Rochelle, NY, September 21, 2018–A new study using antimicrobial susceptibility testing and whole genome sequencing to test extended spectrum beta lactamase (ESBL) producing E. coli isolated from cattle for food production and from various retail meat products has shown that all were resistant to at least three antimicrobial classes. They also carried various types of CTX-M type ESBL genes, which are increasingly common in clinical patients worldwide and whose presence in food-producing animals and retail meat supplies might contribute to a greater incidence of infections. These findings are reported in Microbial Drug Resistance, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers. Click here to read the full-text open access article on the Microbial Drug Resistance website.

Daniel Tadesse, U.S. Food and Drug Administration (FDA, Laurel, MD) and colleagues from the FDA, Texas Tech University (Lubbock, TX), and the U.S. Department of Agriculture (USDA, Clay Center, NE) coauthored the article entitled "Whole Genome Sequence Analysis of CTX-M Containing Escherichia coli Isolates from Retail Meats and Cattle in the United States." The ESBL E. coli isolates from meat samples, including chicken breast, ground turkey, ground beef, and pork chops, were collected by the National Antimicrobial Resistance Monitoring System (NARMS). Antimicrobial susceptibility testing was performed against a panel of 14 antimicrobials and 9 ß-lactam agents.

"This interesting and well-documented paper by Daniel Tadesse and colleagues provides convincing and alarming evidence of the 'arrival' to the dining room table of meat products contaminated by multidrug resistant E. coli, "says Editor-in-Chief Alexander Tomasz, PhD, The Rockefeller University, New York, NY. "This paper brings 'home' the seriousness of the issue of antimicrobial drug resistance."


About the Journal

Microbial Drug Resistance (MDR) is an international, peer-reviewed journal covering the global spread and threat of multi-drug resistant clones of major pathogens that are widely documented in hospitals and the scientific community. Led by Editor-in-Chief Alexander Tomasz, PhD, The Rockefeller University, New York, NY, the Journal addresses the serious challenges of trying to decipher the molecular mechanisms of drug resistance. Complete tables of content and a sample issue may be viewed on the Microbial Drug Resistance website.

About the Publisher

Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including Health Security, Foodborne Pathogens and Disease, and Surgical Infections. Its biotechnology trade magazine, GEN (Genetic Engineering & Biotechnology News), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's more than 85 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website.

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Original Source

https://home.liebertpub.com/news/fda-researchers-report-first-evidence-of-beta-lactamase-producing-antimicrobial-resistant-e-coli-in-us-retail-meat/2429 http://dx.doi.org/10.1089/mdr.2018.0206