FASEB Science Research Conference: Polycystic Kidney Disease

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This SRC focuses on the autosomal dominant (ADPKD) and recessive (ARPKD) forms of PKD, autosomal dominant polycystic liver diseases with mild or no kidney involvement (ADPLD) and syndromic forms of PKD caused by mutations in genes encoding for proteins in the primary cilium (ciliopathies). This SRC will bring together investigators from a wide range of different research areas sharing an interest on PKD and other renal cystic diseases and ciliopathies and promote cross disciplinary discussion and collaboration. The specific goals are: 1) Assemble an interdisciplinary program of basic scientists and clinical researchers that are at the forefront of PKD research to provide a comprehensive update on recent advances in PKD; 2) Provide a format where trainees and junior investigators can present, discuss and learn, with the goal of exciting them about PKD and inspiring them to become the next generation of PKD researchers; 3) Generate a platform for informed discussion to help resolve unanswered questions in PKD and promote collaboration; and 4) Promote the development of novel therapies for PKD by juxtaposing basic scientists, clinical investigators and representations of the pharmaceutical industry.

The program consists of nine oral presentation and two poster sessions, a keynote address on Genome Editing for Monogenic Diseases and a special lecture on the Regulatory Path to Drug Approval in Inherited Slowly Progressive Renal Diseases. Eight oral presentation sessions are structured around a theme: 1) Genetic mechanisms; 2) Cell biology of PKD proteins, extracellular vesicles and cilia; 3) Epigenetics and microRNAs; 4) Cilia, calcium, and cAMP signaling; 5) Other pathways and model systems; 6) Disease mechanisms in other tissues and organs; 7) Cell metabolism and metabolomics; 8) Biomarkers and clinical trials. The ninth session is for late breaking abstracts.

Particular attention in the organization of this Conference is given to including new speakers and speakers from related fields, widening the knowledge of PKD investigators, promoting networking of young investigators with established investigators, and supporting the participation of woman scientists, individuals from underrepresented minorities, and researchers with disabilities. To promote participation of young investigators, PKD laboratories around the world and the PKD Foundation will be contacted to encourage young scientists to submit abstracts. Young scientists, will be encouraged to participate in a "Meet the Expert" session and a Career-Oriented Workshop.

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Media Contact

Robin Crawford
[email protected]
301-634-7010
@fasebopa

http://www.faseb.org

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