Evaluating tissue response to biomaterials with a new bone-implant interaction model
New Rochelle, NY, January 5, 2017–To understand the molecular mechanisms involved in the interaction of bone with orthopedic implants comprised of novel biomaterials, researchers have made a mouse model in which they can assess early tissue responses to surfaces such as bioactive glass. The ease of genetically modifying this mouse model makes it especially valuable in designing novel biomaterials for use in regenerative medicine, as describe in an article published in Tissue Engineering, Part C Methods, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the Tissue Engineering website until February 5, 2017.
The article entitled "A Bone-Implant Interaction Mouse Model for Evaluating Molecular Mechanism of Biomaterials/Bone Interaction" is coauthored by Wenlong Liu, PhD and colleagues from Shenzen Institutes of Advanced Technology, Chinese Academy of Sciences, The University of Hong Kong, and The Chinese University of Hong Kong, Shenzhen, China. They present results demonstrating the feasibility and reliability of the mouse model using various biomaterials.
"This very accessible and elegant model brings the assessment of bone replacing biomaterial to a new level," says Tissue Engineering, Part C: Methods Co-Editor-in-Chief John A. Jansen, DDS, PhD, Professor Dentistry – Biomaterials, Radboud University Medical Center, Nijmegen, Netherlands.
About the Journal
Tissue Engineering is an authoritative peer-reviewed journal published monthly online and in print in three parts: Part A, the flagship journal published 24 times per year; Part B: Reviews, published bimonthly, and Part C: Methods, published 12 times per year. Led by Co-Editors-In-Chief Antonios G. Mikos, PhD, Louis Calder Professor at Rice University, Houston, TX, and Peter C. Johnson, MD, Principal, MedSurgPI, LLC and President and CEO, Scintellix, LLC, Raleigh, NC, the Journal brings together scientific and medical experts in the fields of biomedical engineering, material science, molecular and cellular biology, and genetic engineering. Tissue Engineering is the official journal of the Tissue Engineering & Regenerative Medicine International Society (TERMIS). Complete tables of content and a sample issue may be viewed online at the Tissue Engineering website.
About the Publisher
Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including Stem Cells and Development, Human Gene Therapy, and Advances in Wound Care. Its biotechnology trade magazine, GEN (Genetic Engineering & Biotechnology News (http://www.genengnews.com/), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 80 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website.