Does the gut microbiome offer new therapeutic options for brain diseases?


The surprising and potentially wide-ranging effects that the levels and diversity of bacteria living in the gut have on overall human health, inflammation, and specifically brain health are the focus of a provocative interview with Dr. David Perlmutter in Alternative and Complementary Therapies, a journal from Mary Ann Liebert, Inc., publishers. The article is available free on the Alternative and Complementary Therapies website until August 8, 2016.

In the interview, "The Role of Microbiome Diversity in Brain Health and Inflammation," David Perlmutter, MD, FACN, ABIHM, University of Miami School of Medicine, FL, discusses the role of the microbiome in conditions such as Alzheimer's disease, amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), and autism. He points to ALS as an example of how research on the underlying cause of certain diseases may be shifting from a focus on the brain to the gut. Future treatments for diseases such as ALS could involve fecal transplants to restore the integrity and correct the balance of bacterial composition of the intestines.

Regarding the link between the microbiome and Alzheimer's disease, autoimmune and inflammatory disorders, and the overuse of antibiotics to treat infection, Dr. Perlmutter states, "I hypothesize that our diets today are affecting our microbiomes and therefore challenging our immune systems. Our diets are setting us up for these opportunistic issues [infections]."


About the Journal

Alternative and Complementary Therapies is a bimonthly journal that publishes original articles, reviews, and commentaries evaluating alternative therapies and how they can be integrated into clinical practice. Topics include botanical medicine, vitamins and supplements, nutrition and diet, mind-body medicine, acupuncture and traditional Chinese medicine, ayurveda, indigenous medicine systems, homeopathy, naturopathy, yoga and meditation, manual therapies, energy medicine, and spirituality and health. Complete tables of content and a sample issue may be viewed on the Alternative and Complementary Therapies website.

About the Publisher

Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including The Journal of Alternative and Complementary Medicine, Medical Acupuncture, and Journal of Medicinal Food. Its biotechnology trade magazine, GEN (Genetic Engineering & Biotechnology News), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 80 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website.

Media Contact

Kathryn Ryan

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