Thursday, September 28, 2023
SCIENMAG: Latest Science and Health News
No Result
View All Result
  • Login
  • HOME PAGE
  • BIOLOGY
  • CHEMISTRY AND PHYSICS
  • MEDICINE
    • Cancer
    • Infectious Emerging Diseases
  • SPACE
  • TECHNOLOGY
  • CONTACT US
  • HOME PAGE
  • BIOLOGY
  • CHEMISTRY AND PHYSICS
  • MEDICINE
    • Cancer
    • Infectious Emerging Diseases
  • SPACE
  • TECHNOLOGY
  • CONTACT US
No Result
View All Result
Scienmag - Latest science news from science magazine
No Result
View All Result
Home Latest News

Does maternal obesity during pregnancy impact offspring’s liver and skeletal muscle metabolism?

November 23, 2022
in Latest News
0
Share on FacebookShare on Twitter

A recent study in The FASEB Journal has identified metabolic perturbations in the liver and skeletal muscle of young nonhuman primates on normal diets whose mothers were obese during pregnancy.

For the study, tissue biopsies were obtained from 19 post-pubertal offspring of mothers who were fed a Western diet and were obese during pregnancy, and from 13 control animals born to non-obese mothers fed a standard diet. All offspring ate a healthy chow diet after weaning. Investigators identified 58 metabolites significantly altered in liver and 46 in skeletal muscle of the offspring of mothers with obesity during pregnancy, with 8 metabolites shared between both tissues. Several metabolic pathways were identified from these dysregulated metabolites. These differences in metabolites were not seen in blood samples taken from the animals.

“This study is exciting for two reasons: First it shows that exposure to an unhealthy environment in utero has long-term health consequences, and different organs and tissues are affected in different ways.” said corresponding author Michael Olivier, PhD, of Wake Forest University School of Medicine. “Second, our analysis suggests you cannot just analyze blood samples to understand what is happening in the liver or muscle.”

URL upon publication: https://onlinelibrary.wiley.com/doi/10.1096/fj.202201473R

 

Additional Information

NOTE: The information contained in this release is protected by copyright. Please include journal attribution in all coverage. For more information or to obtain a PDF of any study, please contact: Sara Henning-Stout, newsroom@wiley.com.

About the Journal

The FASEB Journal publishes high quality and impactful multidisciplinary research covering biology and biomedical sciences at every level of organization: atomic, molecular, cell, tissue, organ, organismic, and population. The journal’s scope includes the spectrum of biological and biomedical sciences as well as interdisciplinary research cutting across multiple fields and extending in related areas. The FASEB Journal welcomes manuscripts on basic and translational research as well as on pre-clinical and early clinical research.

About Wiley

Wiley is one of the world’s largest publishers and a global leader in scientific research and career-connected education. Founded in 1807, Wiley enables discovery, powers education, and shapes workforces. Through its industry-leading content, digital platforms, and knowledge networks, the company delivers on its timeless mission to unlock human potential. Visit us at Wiley.com. Follow us on Facebook, Twitter, LinkedIn and Instagram.



Journal

The FASEB Journal

DOI

10.1096/fj.202201473R

Article Title

Maternal obesity alters offspring liver and skeletal muscle metabolism in early post-puberty despite maintaining a normal post-weaning dietary lifestyle

Article Publication Date

23-Nov-2022

Tags: impactLivermaternalmetabolismmuscleobesityoffspringspregnancyskeletal
Share25Tweet16Share4ShareSendShare
  • Null results research now published by major behavioral medicine journal

    1059 shares
    Share 424 Tweet 265
  • Important additional driver of insect decline identified: Weather explains the decline and rise of insect biomass over 34 years

    70 shares
    Share 28 Tweet 18
  • Fish reveal cause of altered human facial development

    67 shares
    Share 27 Tweet 17
  • New study definitively confirms gulf stream weakening, understanding the changes could help predict future trends in extreme events

    69 shares
    Share 28 Tweet 17
  • New findings on hair loss in men

    82 shares
    Share 33 Tweet 21
  • UCLA-led team develops key improvement to Nobel Prize-winning technology

    64 shares
    Share 26 Tweet 16
ADVERTISEMENT

About us

We bring you the latest science news from best research centers and universities around the world. Check our website.

Latest NEWS

Null results research now published by major behavioral medicine journal

New findings on hair loss in men

Important additional driver of insect decline identified: Weather explains the decline and rise of insect biomass over 34 years

Subscribe to Blog via Email

Enter your email address to subscribe to this blog and receive notifications of new posts by email.

Join 208 other subscribers

© 2023 Scienmag- Science Magazine: Latest Science News.

No Result
View All Result
  • HOME PAGE
  • BIOLOGY
  • CHEMISTRY AND PHYSICS
  • MEDICINE
    • Cancer
    • Infectious Emerging Diseases
  • SPACE
  • TECHNOLOGY
  • CONTACT US

© 2023 Scienmag- Science Magazine: Latest Science News.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In