Friday, May 20, 2022
SCIENMAG: Latest Science and Health News
No Result
View All Result
  • Login
  • HOME PAGE
  • BIOLOGY
  • CHEMISTRY AND PHYSICS
  • MEDICINE
    • Cancer
    • Infectious Emerging Diseases
  • SPACE
  • TECHNOLOGY
  • CONTACT US
  • HOME PAGE
  • BIOLOGY
  • CHEMISTRY AND PHYSICS
  • MEDICINE
    • Cancer
    • Infectious Emerging Diseases
  • SPACE
  • TECHNOLOGY
  • CONTACT US
No Result
View All Result
Scienmag - Latest science news from science magazine
No Result
View All Result
Home SCIENCE NEWS Technology and Engineering

Destroying cancer cells with non-surgical ultrasound treatment

October 26, 2020
in Technology and Engineering
0
Share on FacebookShare on Twitter

Demonstrated the mechanism behind the secondary generation of cavitation clouds that mechanically fractionates surrounding tissue in focused ultrasound treatment. Laid the groundwork for precise removal of the target tissue.

IMAGE

Credit: Korea Institue of Science and Technology(KIST)

Focusing ultrasound energy on a target site in the body to generate heat can burn and destroy the tissue in the site without a surgical procedure. This method is clinically applied to treat uterine fibroids, prostatic hyperplasia, prostate cancer, metastatic bone tumor and other types of tumor to destroy tumor cells using heat. However, there is a potential problem that the surrounding tissue may be burned in the process due to heat diffusion.

In 2019, at the Korea Institute of Science and Technology (KIST) Center for Bionics, Dr. Ki Joo Pahk’s research team confirmed the possibility of precisely fractionating target tumor cells, as though it is cut out using a knife, without causing heat damage to any other part of the body by using high-intensity focused ultrasound (HIFU), an ultrasound with an acoustic pressure in megapascals (MPa) that is much more powerful than existing ultrasound, and revealed the mechanism behind the procedure.(?Ultrasonics Sonochemistry. 2019, 53, 164-177)

In the process of physically destroying the tissue without the use of heat, a boiling vapor bubble is generated at the target site of the HIFU, and it is by the kinetic energy of this primary vapor bubble that the target tumor tissue gets destroyed. However, during the process, cavitation bubble clouds can be subsequently generated between the boiling bubble and the HIFU transducer, leading to unwanted cell destruction. This made it necessary to identify the cause of their formation and to accurately predict the locations of their occurrence.

In order to reveal the mechanism of cavitation bubble clouds formation occurring when tumor tissue is removed by HIFU, the research team at KIST developed a mathematical model as part of their follow-up study and examined the impact of the primary boiling vapor bubble on nonlinear wave propagation. The results showed that the secondary generation of bubbles was caused by a constructive interference of the backscattered shockwave by the boiling bubble with the incoming incident shockwaves and it is within the range of this interference that the secondary bubbles formed. Based on the images obtained using a high-speed camera, it was found that the area where the interference occurred and the area where the secondary bubbles were generated were closely matched.

These findings not only explain the mechanism behind the secondary bubbles formation but also help predict where they will occur, thereby presenting the possibility of destroying target tissue with greater safety and precision.

Dr. Pahk from KIST said, “This study has shown that cavitation bubble clouds can be subsequently generated as a result of a shock scattering effect after a boiling vapor bubble forms where the ultrasound is focused. Using the mathematical developed in this study, it will be possible to predict the locations of bubble formation and the potential site that gets destroyed. I hope that the ultrasound technology under development will be developed in an ultra-precision focused ultrasound technology enabling physical destruction of only the tumor tissue, without the need for surgery, so that it can be applied clinically in the future.”

###

This study was carried out with a grant from the Ministry of Science and ICT (MSIT), as part of the Institutional R&D Program of KIST and the Creative Convergence Research Program of the National Research Council of Science & Technology (NST). It was published in the latest edition of Ultrasonics Sonochemistry (IF: 6.513, Top 1.562% in the field of JCR), a leading international journal in the field of acoustics.

Media Contact
Do-Hyun Kim
[email protected]

Related Journal Article

http://dx.doi.org/10.1016/j.ultsonch.2020.105312

Tags: BiologyMedicine/HealthTechnology/Engineering/Computer Science
Share26Tweet16Share4ShareSendShare
  • Sofie Nyström and Per Hammarström

    Possible discovery of mechanism behind mysterious COVID-19 symptoms

    68 shares
    Share 27 Tweet 17
  • Researchers discover genetic cause of megaesophagus in dogs

    1025 shares
    Share 410 Tweet 256
  • Some people fared better than others during COVID-19 pandemic due to genetics

    67 shares
    Share 27 Tweet 17
  • Do early therapies help very young children with or at high likelihood for autism?

    69 shares
    Share 28 Tweet 17
  • Study tests link between common blood pressure pills and breast cancer

    66 shares
    Share 26 Tweet 17
  • What the new Jurassic Park movie gets wrong: Aerodynamic analysis causes a rethink of the biggest pterosaur.

    65 shares
    Share 26 Tweet 16
ADVERTISEMENT

About us

We bring you the latest science news from best research centers and universities around the world. Check our website.

Latest NEWS

Understanding how sunscreens damage coral

SUTD develops design-based activity to enhance students’ understanding in electrochemistry

New Curtin research resurrects ‘lost’ coral species

Subscribe to Blog via Email

Enter your email address to subscribe to this blog and receive notifications of new posts by email.

Join 187 other subscribers

© 2022 Scienmag- Science Magazine: Latest Science News.

No Result
View All Result
  • HOME PAGE
  • BIOLOGY
  • CHEMISTRY AND PHYSICS
  • MEDICINE
    • Cancer
    • Infectious Emerging Diseases
  • SPACE
  • TECHNOLOGY
  • CONTACT US

© 2022 Scienmag- Science Magazine: Latest Science News.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
Posting....