Concussions in adolescence linked with an increased risk of multiple sclerosis

A new study published in the Annals of Neurology found a link between head trauma in adolescence, particularly if repeated, with a raised risk of later developing multiple sclerosis. The link may be due to the initiation of an autoimmune process in the central nervous system.

In the analysis of 7292 patients from Sweden with multiple sclerosis who were each matched with 10 people without the condition, one diagnosed concussion in adolescence was associated with a 22% increased likelihood of developing multiple sclerosis. More than one concussion was associated with a greater than twofold increased likelihood.

"This is yet another reason to protect adolescents from head injury, particularly where they are at risk of repeated trauma, including from sports-related injuries," said Prof. Scott Montgomery, lead author of the study.


Additional Information

Media Contacts:

Dawn Peters (US), Wiley
P: +1 781-388-8408
[email protected]
Follow us on Twitter @WileyNews

Citation: Montgomery, S., Hiyoshi, A., Burkill, S., Alfredsson, L., Bahmanyar, S. and Olsson, T. (), Concussion in adolescence and risk of multiple sclerosis. Ann Neurol. doi:10.1002/ana.25036.

About Wiley

Wiley, a global company, helps people and organizations develop the skills and knowledge they need to succeed. Our online scientific, technical, medical, and scholarly journals, combined with our digital learning, assessment and certification solutions help universities, learned societies, businesses, governments and individuals increase the academic and professional impact of their work. For more than 200 years, we have delivered consistent performance to our stakeholders. The company's website can be accessed at

Media Contact

Dawn Peters
[email protected]

%d bloggers like this: