A new study published in Cancer Medicine indicates that exosomes, or small bubbles that transport molecules from one cell to another, can be effective vehicles for delivering cancer treatments to tumors.
In the study, researchers used exosomes produced by cells called adipose-derived mesenchymal stem cells (ADSCs) to deliver an RNA-based anti-cancer treatment (miR-138-5p) to bladder cancer tumors in mice.
“The present results reveal that ADSC-derived exosomes are an effective delivery vehicle for small molecule drugs in vivo, and exosome-delivered miR-138-5p is a promising therapeutic agent for bladder cancer treatment,” the authors wrote.
Cancer Medicine is pleased to announce its new Editor-in-Chief, Dr. Stephen Tait of the University of Glasgow, UK, and Co-Editors, Dr. Alfred Lam of Griffith University, Australia and Dr. Maryam Lustberg of Yale University, USA. With this change, the journal is also happy to announce the appointment of several new Associate Editors.
URL Upon Publication: https://onlinelibrary.wiley.com/doi/10.1002/cam4.4745
NOTE: The information contained in this release is protected by copyright. Please include journal attribution in all coverage. For more information or to obtain a PDF of any study, please contact:
About the Journal
Cancer Medicine is a peer-reviewed, open access, interdisciplinary journal providing rapid publication of research from global biomedical researchers across the cancer sciences, in the areas of, but not limited to, cancer biology, clinical cancer research, and cancer prevention.
Wiley is a global leader in research and education, unlocking human potential by enabling discovery, powering education, and shaping workforces. For over 200 years, Wiley has fueled the world’s knowledge ecosystem. Today, our high-impact content, platforms, and services help researchers, learners, institutions, and corporations achieve their goals in an ever-changing world. Visit us at Wiley.com, like us on Facebook and follow us on Twitter and LinkedIn.
Evaluating adipose-derived stem cell exosomes as miRNA drug delivery systems for the treatment of bladder cancer
Article Publication Date