Can stress testing and biomarker studies predict cardiovascular event risk in older women?

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Credit: Mary Ann Liebert, Inc., publishers

New Rochelle, NY, May 1, 2018–Mayo Clinic researchers, reporting results of the SMART study, have shown that abnormal results on a stress electrocardiogram are an independent predictor of cardiovascular events such as heart attack, heart failure, hospitalization for chest pain, and death in perimenopausal or menopausal women. The study, which also demonstrated the predictive value of the blood biomarker brain natriuretic peptide (BNP), is published in Journal of Women's Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers. The article is available free on the Journal of Women's Health website.

The article "Prognostic Utility of Stress Testing and Cardiac Biomarkers in Menopausal Women at Low to Intermediate Risk for Coronary ARTery Disease (SMART Study): 5-Year Outcomes" is coauthored by Sharon Mulvagh, MD, Mayo Clinic (Rochester, MN) and Dalhousie University (Halifax, Canada) and colleagues from Mayo Clinic (MN and Phoenix, AZ), Memorial Hospital (Jacksonville, FL), Assiut University (Egypt), and Arcispedale Santa Maria Nuova (Reggio Emilia, Italy). This prospective study evaluated the predictive value of stress testing and cardiac biomarkers over a 5-year follow-up period in women who were at low-to-intermediate risk of a cardiovascular event.

"Clinicians need effective and proven noninvasive tools to assess women of low-to-moderate risk of a cardiovascular event who present with chest pain and related symptoms," says Susan G. Kornstein, MD, Editor-in-Chief of Journal of Women's Health, Executive Director of the Virginia Commonwealth University Institute for Women's Health, Richmond, VA, and President of the Academy of Women's Health. "In this study, Mulvagh et al. established the predictive value of stress ECG and resting BNP and emphasize the importance of future research to discover cardiac biomarkers of myocardial ischemia at earlier stages in women."

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About the Journal

Journal of Women's Health, published monthly, is a core multidisciplinary journal dedicated to the diseases and conditions that hold greater risk for or are more prevalent among women, as well as diseases that present differently in women. Led by Editor-in-Chief Susan G. Kornstein, MD, Executive Director of the Virginia Commonwealth University Institute for Women's Health, Richmond, VA, and President of the Academy of Women's Health, the Journal covers the latest advances and clinical applications of new diagnostic procedures and therapeutic protocols for the prevention and management of women's healthcare issues. Complete tables of content and a sample issue may be viewed on the Journal of Women's Health website. Journal of Women's Health is the official journal of the Academy of Women's Health and the Society for Women's Health Research.

About the Academy

Academy of Women's Health is an interdisciplinary, international association of physicians, nurses, and other health professionals who work across the broad field of women's health, providing its members with up-to-date advances and options in clinical care that will enable the best outcomes for their women patients. The Academy's focus includes the dissemination of translational research and evidence-based practices for disease prevention, diagnosis, and treatment of women across the lifespan.

About the Publisher

Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including LGBT Health, Transgender Health, Population Health Management, and Breastfeeding Medicine. Its biotechnology trade magazine, GEN (Genetic Engineering & Biotechnology News), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 80 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website.

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Original Source

https://home.liebertpub.com/news/can-stress-testing-and-biomarker-studies-predict-cardiovascular-event-risk-in-older-women/2375 http://dx.doi.org/10.1089/jwh.2017.6506

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