Baker’s yeast helped MSU-based biologists to understand drug resistance in fungi

(Lomonosov Moscow State University) MSU-based biologists advanced in understanding of fungal drug resistance mechanisms. To study them the scientists used baker's yeast expressing fluorescent proteins fused with the membrane transporters. Fungi activate the protection mechanisms in response to accumulation of toxic compounds in their cells. The study showed that the resistance of yeast (and possibly pathogenic fungi) to antimycotic agents is more complex than it was previously thought. Its results were published in the Scientific Reports journal.