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3-D-printed polymer stents grow with pediatric patients and biodegrade over time

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Credit: Mary Ann Liebert, Inc., publishers

New Rochelle, NY, May 18, 2017–A new study demonstrates proof-of-concept for combining computational design and simulation tools with 3D printing technology to produce self-expandable polymer stents that can grow with pediatric patients, are biodegradable, and require only a minimally-invasive procedure for implantation. This innovative method is described in an article in 3D Printing and Additive Manufacturing, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available open access on the 3D Printing and Additive Manufacturing website.

M.S. Cabrera, B. Sanders, O.J.G.M. Goor, A. Driessen-Mol, C.W.J. Oomens, and F.P.T. Baaijens, Eindhoven University of Technology, the Netherlands, coauthored the study entitled "Computationally Designed 3D Printed Self-Expandable Polymer Stents with Biodegradation Capacity for Minimally-Invasive Heart Valve Implantation: A Proof of Concept Study."

To overcome the current challenges in designing bioabsorbable polymer stents with the necessary mechanical properties for use in minimally invasive procedures to implant tissue-engineered heart valves in young patients, researchers have developed a novel approach to create stents with growth potential and a sufficient degree of plastic deformation. The rapid prototyping method they describe involves creating an in silico model of a conventional nitinol stent and then translating the computational simulation into prototype stents using 3D printing and a flexible copolyester elastomer. The authors evaluated the mechanical properties of the stents by subjecting them to crush and crimping tests, and performed accelerated degradation tests to assess their biodegradability.

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About the Journal

3D Printing and Additive Manufacturing is the only peer-reviewed journal focused on the rapidly moving field of 3D printing and related technologies. Led by Editor-in-Chief Skylar Tibbits Director, Self-Assembly Lab, MIT, and Founder & Principal, SJET LLC., the Journal explores emerging challenges and opportunities ranging from new developments of processes and materials, to new simulation and design tools, and informative applications and case studies. Published quarterly online with open access options and in print, the Journal spans a broad array of disciplines to address the challenges and discover new breakthroughs and trends within this groundbreaking technology. Tables of content and a sample issue may be viewed on the 3D Printing and Additive Manufacturing website.

About the Publisher

Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative medical and biomedical peer-reviewed journals, including Big Data, Soft Robotics, New Space, and Tissue Engineering. Its biotechnology trade magazine GEN (Genetic Engineering & Biotechnology News) was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's more than 80 journals, newsmagazines, and books is available on the Mary Ann Liebert, Inc., publishers website.

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Danielle Giordano
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Original Source

http://www.liebertpub.com/global/pressrelease/3d-printed-polymer-stents-grow-with-pediatric-patients-and-biodegrade-over-time/2174/ http://dx.doi.org/10.1089/3dp.2016.0052

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